Which of the following is NOT a method of drug excretion from the body?

The correct answer is that digestion is not a method of drug excretion from the body. Drug excretion refers specifically to the processes by which substances are eliminated from the body, primarily after they have been metabolized.

Exhalation, defecation, and sweating are all recognized forms of excretion. Exhalation involves the elimination of volatile substances through the lungs, such as anesthetic gases. Defecation refers to the elimination of substances through the gastrointestinal tract after digestion has occurred, indicating that waste products can also include some unmetabolized drugs. Sweating involves the excretion of substances through the skin, where certain drugs and their metabolites can be released.

Digestion, on the other hand, is the process of breaking down food into its constituent nutrients for absorption and is not involved in the elimination of drugs or their metabolites. Therefore, while the body may process drugs in the digestive system, the act of digestion itself does not contribute to excretion.